{"id":42790,"date":"2024-03-06T16:05:17","date_gmt":"2024-03-06T12:05:17","guid":{"rendered":"https:\/\/ictimai.az\/?p=42790"},"modified":"2024-03-06T15:24:07","modified_gmt":"2024-03-06T11:24:07","slug":"alimler-medealti-vezi-xercenginin-mualicesi-ucun-yeni-derman-hazirlayiblar","status":"publish","type":"post","link":"https:\/\/ictimai.az\/?p=42790","title":{"rendered":"Aliml\u0259r m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259nginin m\u00fcalic\u0259si \u00fc\u00e7\u00fcn yeni d\u0259rman haz\u0131rlay\u0131blar"},"content":{"rendered":"<p>San-Fransiskodak\u0131 Kaliforniya Universitetinin aliml\u0259ri m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi hallar\u0131n\u0131n dem\u0259k olar ki, yar\u0131s\u0131ndan m\u0259sul olan K-Ras G12D adl\u0131 mutasiyan\u0131 yat\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar. Onlar t\u0259dqiqatlar\u0131n\u0131n n\u0259tic\u0259l\u0259rini Nature Chemical Biology jurnal\u0131nda payla\u015f\u0131blar.<\/p>\n<p>Aliml\u0259r qeyd edibl\u0259r ki, m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi dig\u0259rl\u0259rin\u0259 nisb\u0259t\u0259n daha az rast g\u0259linir v\u0259 bu, effektiv m\u00fcalic\u0259 variantlar\u0131n\u0131n kifay\u0259t q\u0259d\u0259r se\u00e7ilm\u0259m\u0259sinin dolay\u0131 s\u0259b\u0259bidir. Bu bilik bo\u015flu\u011funu doldurmaq \u00fc\u00e7\u00fcn t\u0259dqiqat\u00e7\u0131lar si\u00e7anlar \u00fcz\u0259rind\u0259 \u00e7oxsayl\u0131 t\u0259cr\u00fcb\u0259l\u0259r apard\u0131lar. Onlar m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi hallar\u0131n\u0131n dem\u0259k olar ki, yar\u0131s\u0131na cavabdeh olan K-Ras G12D mutasiyas\u0131n\u0131 yat\u0131ra bil\u0259n prototip d\u0259rman haz\u0131rlaya bildil\u0259r.<\/p>\n<p>T\u0259dqiqat\u00e7\u0131lar izah etdil\u0259r ki, K-Ras n\u00f6vl\u0259ri m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngind\u0259 son d\u0259r\u0259c\u0259 yayg\u0131nd\u0131r &#8211; hallar\u0131n 90% -ind\u0259 ba\u015f verir. Bu K-Ras mutasiyalar\u0131n\u0131n t\u0259xmin\u0259n yar\u0131s\u0131 G12D-dir ki, bu da \u0259ks\u0259r dig\u0259rl\u0259rind\u0259n bir amin tur\u015fusu d\u0259yi\u015fikliyi il\u0259 f\u0259rql\u0259nir. Bu f\u0259rq sa\u011flam v\u0259 x\u0259r\u00e7\u0259ng\u0259 s\u0259b\u0259b olan z\u00fclallar aras\u0131nda \u0259sasd\u0131r, \u00e7\u00fcnki amin tur\u015fular\u0131n\u0131n d\u0259yi\u015fdirilm\u0259si qlisini aspartata \u00e7evirir.<\/p>\n<p>M\u0259nb\u0259: Lenta.ru<\/p>\n","protected":false},"excerpt":{"rendered":"<p>San-Fransiskodak\u0131 Kaliforniya Universitetinin aliml\u0259ri m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi hallar\u0131n\u0131n dem\u0259k olar ki, yar\u0131s\u0131ndan m\u0259sul olan K-Ras G12D adl\u0131 mutasiyan\u0131 yat\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar. Onlar t\u0259dqiqatlar\u0131n\u0131n n\u0259tic\u0259l\u0259rini Nature Chemical Biology jurnal\u0131nda payla\u015f\u0131blar. Aliml\u0259r qeyd edibl\u0259r ki, m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi dig\u0259rl\u0259rin\u0259 nisb\u0259t\u0259n daha az rast g\u0259linir v\u0259 bu, effektiv m\u00fcalic\u0259 variantlar\u0131n\u0131n kifay\u0259t q\u0259d\u0259r se\u00e7ilm\u0259m\u0259sinin dolay\u0131 s\u0259b\u0259bidir. Bu bilik [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":42791,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,41],"tags":[],"class_list":["post-42790","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-media","category-life"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Aliml\u0259r m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259nginin m\u00fcalic\u0259si \u00fc\u00e7\u00fcn yeni d\u0259rman haz\u0131rlay\u0131blar - \u0130CT\u0130MA\u0130.AZ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ictimai.az\/?p=42790\" \/>\n<meta property=\"og:locale\" content=\"az_AZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Aliml\u0259r m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259nginin m\u00fcalic\u0259si \u00fc\u00e7\u00fcn yeni d\u0259rman haz\u0131rlay\u0131blar - \u0130CT\u0130MA\u0130.AZ\" \/>\n<meta property=\"og:description\" content=\"San-Fransiskodak\u0131 Kaliforniya Universitetinin aliml\u0259ri m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi hallar\u0131n\u0131n dem\u0259k olar ki, yar\u0131s\u0131ndan m\u0259sul olan K-Ras G12D adl\u0131 mutasiyan\u0131 yat\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar. Onlar t\u0259dqiqatlar\u0131n\u0131n n\u0259tic\u0259l\u0259rini Nature Chemical Biology jurnal\u0131nda payla\u015f\u0131blar. Aliml\u0259r qeyd edibl\u0259r ki, m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi dig\u0259rl\u0259rin\u0259 nisb\u0259t\u0259n daha az rast g\u0259linir v\u0259 bu, effektiv m\u00fcalic\u0259 variantlar\u0131n\u0131n kifay\u0259t q\u0259d\u0259r se\u00e7ilm\u0259m\u0259sinin dolay\u0131 s\u0259b\u0259bidir. 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Onlar t\u0259dqiqatlar\u0131n\u0131n n\u0259tic\u0259l\u0259rini Nature Chemical Biology jurnal\u0131nda payla\u015f\u0131blar. Aliml\u0259r qeyd edibl\u0259r ki, m\u0259d\u0259alt\u0131 v\u0259zi x\u0259r\u00e7\u0259ngi dig\u0259rl\u0259rin\u0259 nisb\u0259t\u0259n daha az rast g\u0259linir v\u0259 bu, effektiv m\u00fcalic\u0259 variantlar\u0131n\u0131n kifay\u0259t q\u0259d\u0259r se\u00e7ilm\u0259m\u0259sinin dolay\u0131 s\u0259b\u0259bidir. 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