Avropa Bioinformatika \u0130nstitutunun v\u0259 London Universitet Kollecinin aliml\u0259ri m\u00fc\u0259yy\u0259n edibl\u0259r ki, y\u00fcks\u0259k d\u0259r\u0259c\u0259li osteosarkoma (s\u00fcm\u00fck x\u0259r\u00e7\u0259ngi) hallar\u0131n\u0131n t\u0259xmin\u0259n 50%-i itki-translokasiya-amplifikasiya (LTA) xromotripsisi adl\u0131 mutasiya n\u0259tic\u0259sind\u0259 inki\u015faf edir.<\/p>\n
Ara\u015fd\u0131rman\u0131n n\u0259tic\u0259l\u0259ri Cell jurnal\u0131nda d\u0259rc olunub.<\/p>\n
Osteosarkoma nadir v\u0259 aqressiv x\u0259st\u0259likdir v\u0259 \u0259n \u00e7ox on ya\u015fdan 20 ya\u015fa q\u0259d\u0259r olan u\u015faq v\u0259 yeniyetm\u0259l\u0259ri t\u0259sir edir, s\u00fcm\u00fckl\u0259rin intensiv b\u00f6y\u00fcm\u0259si d\u00f6vr\u00fcd\u00fcr. B\u0259dxass\u0259li s\u00fcm\u00fck \u015fi\u015fl\u0259rinin inki\u015faf\u0131 tez-tez c\u0259rrahi m\u00fcdaxil\u0259 v\u0259 b\u0259z\u0259n amputasiya t\u0259l\u0259b edir. Bundan \u0259lav\u0259, s\u00fcm\u00fck x\u0259r\u00e7\u0259ngi dig\u0259r orqanlara, x\u00fcsus\u0259n d\u0259 a\u011fciy\u0259rl\u0259r\u0259 yay\u0131la bil\u0259r.<\/p>\n
Osteosarkoman\u0131n inki\u015faf\u0131n\u0131n genetik mexanizml\u0259rinin m\u00fcr\u0259kk\u0259bliyi s\u0259b\u0259bind\u0259n elm adamlar\u0131 uzun m\u00fcdd\u0259t bu x\u0259st\u0259liy\u0259 s\u0259b\u0259b olan mutasiyalar\u0131 d\u0259qiq m\u00fc\u0259yy\u0259n ed\u0259 bilm\u0259dil\u0259r. N\u0259tic\u0259d\u0259, m\u00fcalic\u0259 \u00fcsullar\u0131 son 40 il \u0259rzind\u0259 dem\u0259k olar ki, d\u0259yi\u015fm\u0259z qalm\u0131\u015fd\u0131r.<\/p>\n
Uzun DNT ard\u0131c\u0131ll\u0131\u011f\u0131ndan istifad\u0259 ed\u0259n son ara\u015fd\u0131rma, osteosarkoma hallar\u0131n\u0131n 50% -nin \u0259sas\u0131n\u0131 t\u0259\u015fkil ed\u0259n LTA xromotripsinin yeni mexanizmini m\u00fc\u0259yy\u0259n etdi. Bu yana\u015fma, x\u0259st\u0259lik zaman\u0131 yenid\u0259n qurulan x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259si xromosomlar\u0131n\u0131n, \u015fi\u015f ir\u0259lil\u0259dikc\u0259 \u0259lav\u0259 anormall\u0131qlar toplamaqda davam etm\u0259si v\u0259 onun m\u00fcalic\u0259d\u0259n yay\u0131nmas\u0131na k\u00f6m\u0259k etm\u0259si il\u0259 ba\u011fl\u0131 fikir verdi.<\/p>\n","protected":false},"excerpt":{"rendered":"
Avropa Bioinformatika \u0130nstitutunun v\u0259 London Universitet Kollecinin aliml\u0259ri m\u00fc\u0259yy\u0259n edibl\u0259r ki, y\u00fcks\u0259k d\u0259r\u0259c\u0259li osteosarkoma (s\u00fcm\u00fck x\u0259r\u00e7\u0259ngi) hallar\u0131n\u0131n t\u0259xmin\u0259n 50%-i itki-translokasiya-amplifikasiya (LTA) xromotripsisi adl\u0131 mutasiya n\u0259tic\u0259sind\u0259 inki\u015faf edir. Ara\u015fd\u0131rman\u0131n n\u0259tic\u0259l\u0259ri Cell jurnal\u0131nda d\u0259rc olunub. Osteosarkoma nadir v\u0259 aqressiv x\u0259st\u0259likdir v\u0259 \u0259n \u00e7ox on ya\u015fdan 20 ya\u015fa q\u0259d\u0259r olan u\u015faq v\u0259 yeniyetm\u0259l\u0259ri t\u0259sir edir, s\u00fcm\u00fckl\u0259rin intensiv b\u00f6y\u00fcm\u0259si […]<\/p>\n","protected":false},"author":3,"featured_media":64127,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,41],"tags":[],"class_list":["post-64126","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-media","category-life"],"yoast_head":"\n