{"id":76766,"date":"2025-10-23T22:25:58","date_gmt":"2025-10-23T18:25:58","guid":{"rendered":"https:\/\/ictimai.az\/?p=76766"},"modified":"2025-10-23T12:46:35","modified_gmt":"2025-10-23T08:46:35","slug":"alimler-prostat-xercengi-genlerini-sondurmeyin-yolunu-tapiblar","status":"publish","type":"post","link":"https:\/\/ictimai.az\/?p=76766","title":{"rendered":"Aliml\u0259r prostat x\u0259r\u00e7\u0259ngi genl\u0259rini “s\u00f6nd\u00fcrm\u0259yin” yolunu tap\u0131blar"},"content":{"rendered":"

Mi\u00e7iqan Universitetinin t\u0259dqiqat\u00e7\u0131lar\u0131 prostat x\u0259r\u00e7\u0259nginin genetik mexanizml\u0259rini bloklayaraq onun b\u00f6y\u00fcm\u0259sini dayand\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar.<\/p>\n

N\u0259tic\u0259l\u0259r Nature Genetics jurnal\u0131nda d\u0259rc olunub.<\/p>\n

T\u0259dqiqat g\u00f6st\u0259rdi ki, b\u0259dxass\u0259li prostat h\u00fcceyr\u0259l\u0259ri \u015fi\u015f b\u00f6y\u00fcm\u0259si “a\u00e7\u0131c\u0131lar\u0131” kimi \u00e7\u0131x\u0131\u015f ed\u0259n g\u00fccl\u0259ndiricil\u0259r adlanan x\u00fcsusi DNT b\u00f6lg\u0259l\u0259rind\u0259n as\u0131l\u0131d\u0131r. Aliml\u0259r bu g\u00fccl\u0259ndiricil\u0259rin \u0259sas kimy\u0259vi markerini – H2BNTac-\u0131n asetill\u0259\u015fm\u0259sini, h\u0259m\u00e7inin onun aktivl\u0259\u015fdirilm\u0259sin\u0259 cavabdeh olan p300 v\u0259 CBP fermentl\u0259rini k\u0259\u015ff etdil\u0259r.<\/p>\n

Bu k\u0259\u015ff \u0259sas\u0131nda komanda p300 v\u0259 CBP fermentl\u0259rini se\u00e7ici \u015f\u0259kild\u0259 pozan CBPD-409 d\u0259rman\u0131 yaratd\u0131. Onlar\u0131 m\u0259hv ed\u0259r\u0259k, d\u0259rman H2BNTac markerini aradan qald\u0131r\u0131r v\u0259 bununla da \u015fi\u015f b\u00f6y\u00fcm\u0259sinin \u0259sas h\u0259r\u0259k\u0259tvericil\u0259ri olan androgen reseptorlar\u0131n\u0131n f\u0259aliyy\u0259tini bo\u011fur.<\/p>\n

H\u00fcceyr\u0259 m\u0259d\u0259niyy\u0259tl\u0259ri v\u0259 heyvan modell\u0259ri \u00fcz\u0259rind\u0259 apar\u0131lan t\u0259cr\u00fcb\u0259l\u0259rd\u0259 d\u0259rman prostat x\u0259r\u00e7\u0259nginin m\u00fcalic\u0259y\u0259 davaml\u0131 formalar\u0131n\u0131n inki\u015faf\u0131n\u0131 dayand\u0131rd\u0131 v\u0259 n\u0259z\u0259r\u0259 \u00e7arpan yan t\u0259sirl\u0259r olmadan \u015fi\u015fin reqressiyas\u0131na s\u0259b\u0259b oldu.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mi\u00e7iqan Universitetinin t\u0259dqiqat\u00e7\u0131lar\u0131 prostat x\u0259r\u00e7\u0259nginin genetik mexanizml\u0259rini bloklayaraq onun b\u00f6y\u00fcm\u0259sini dayand\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar. N\u0259tic\u0259l\u0259r Nature Genetics jurnal\u0131nda d\u0259rc olunub. T\u0259dqiqat g\u00f6st\u0259rdi ki, b\u0259dxass\u0259li prostat h\u00fcceyr\u0259l\u0259ri \u015fi\u015f b\u00f6y\u00fcm\u0259si “a\u00e7\u0131c\u0131lar\u0131” kimi \u00e7\u0131x\u0131\u015f ed\u0259n g\u00fccl\u0259ndiricil\u0259r adlanan x\u00fcsusi DNT b\u00f6lg\u0259l\u0259rind\u0259n as\u0131l\u0131d\u0131r. Aliml\u0259r bu g\u00fccl\u0259ndiricil\u0259rin \u0259sas kimy\u0259vi markerini – H2BNTac-\u0131n asetill\u0259\u015fm\u0259sini, h\u0259m\u00e7inin onun aktivl\u0259\u015fdirilm\u0259sin\u0259 cavabdeh olan p300 v\u0259 CBP […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,41],"tags":[],"class_list":["post-76766","post","type-post","status-publish","format-standard","hentry","category-media","category-life"],"yoast_head":"\nAliml\u0259r prostat x\u0259r\u00e7\u0259ngi genl\u0259rini "s\u00f6nd\u00fcrm\u0259yin" yolunu tap\u0131blar - \u0130CT\u0130MA\u0130.AZ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ictimai.az\/?p=76766\" \/>\n<meta property=\"og:locale\" content=\"az_AZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Aliml\u0259r prostat x\u0259r\u00e7\u0259ngi genl\u0259rini "s\u00f6nd\u00fcrm\u0259yin" yolunu tap\u0131blar - \u0130CT\u0130MA\u0130.AZ\" \/>\n<meta property=\"og:description\" content=\"Mi\u00e7iqan Universitetinin t\u0259dqiqat\u00e7\u0131lar\u0131 prostat x\u0259r\u00e7\u0259nginin genetik mexanizml\u0259rini bloklayaraq onun b\u00f6y\u00fcm\u0259sini dayand\u0131ra bil\u0259n d\u0259rman haz\u0131rlay\u0131blar. N\u0259tic\u0259l\u0259r Nature Genetics jurnal\u0131nda d\u0259rc olunub. T\u0259dqiqat g\u00f6st\u0259rdi ki, b\u0259dxass\u0259li prostat h\u00fcceyr\u0259l\u0259ri \u015fi\u015f b\u00f6y\u00fcm\u0259si “a\u00e7\u0131c\u0131lar\u0131” kimi \u00e7\u0131x\u0131\u015f ed\u0259n g\u00fccl\u0259ndiricil\u0259r adlanan x\u00fcsusi DNT b\u00f6lg\u0259l\u0259rind\u0259n as\u0131l\u0131d\u0131r. 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