Karolinska \u0130nstitutunun aliml\u0259ri qocalm\u0131\u015f onur\u011fa beynind\u0259 g\u00f6zl\u0259nilm\u0259z bir qoruyucu mexanizm k\u0259\u015ff edibl\u0259r: onun \u00f6z immun h\u00fcceyr\u0259l\u0259ri sinir lifl\u0259rin\u0259 d\u0259y\u0259n z\u0259r\u0259rin qar\u015f\u0131s\u0131n\u0131 alma\u011fa k\u00f6m\u0259k edir.<\/p>\n
T\u0259dqiqat\u0131n n\u0259tic\u0259l\u0259ri Nature Neuroscience jurnal\u0131nda d\u0259rc edilib.<\/p>\n
Ya\u015fla, beyin v\u0259 b\u0259d\u0259n aras\u0131nda siqnal \u00f6t\u00fcr\u0259n onur\u011fa beyni t\u0259dric\u0259n struktur b\u00fct\u00f6vl\u00fcy\u00fcn\u00fc itirir. Sinir lifl\u0259rini \u0259hat\u0259 ed\u0259n qoruyucu t\u0259b\u0259q\u0259 olan miyelin x\u00fcsusil\u0259 h\u0259ssasd\u0131r. M\u00fcxt\u0259lif ya\u015fda olan si\u00e7anlar\u0131 ara\u015fd\u0131ran t\u0259dqiqat\u00e7\u0131lar onur\u011fa beyninin dorsal s\u00fctunlar\u0131ndak\u0131 miyelinin zamanla z\u0259d\u0259l\u0259ndiyini a\u015fkar edibl\u0259r.<\/p>\n
T\u0259dqiqat g\u00f6st\u0259rib ki, mikroqliya bu d\u0259yi\u015fiklikl\u0259r\u0259 cavab verm\u0259kd\u0259 \u0259sas rol oynay\u0131r. Qocalm\u0131\u015f onur\u011fa beynind\u0259 bu h\u00fcceyr\u0259l\u0259r siqnal molekulu TGF-\u03b2-n\u0131 aktivl\u0259\u015fdirir. O, bir n\u00f6v \u0259yl\u0259c kimi \u00e7\u0131x\u0131\u015f edir, h\u0259ddind\u0259n art\u0131q mikroqliya f\u0259aliyy\u0259tini m\u0259hdudla\u015fd\u0131r\u0131r v\u0259 miyelinin daha da m\u0259hv olmas\u0131n\u0131n qar\u015f\u0131s\u0131n\u0131 al\u0131r.<\/p>\n
Aliml\u0259r ya\u015fl\u0131 si\u00e7anlarda TGF-\u03b2 istehsal\u0131n\u0131 eksperimental olaraq dayand\u0131rd\u0131qda, qoruyucu mexanizm f\u0259aliyy\u0259tini dayand\u0131rd\u0131. Mikroqliya miyelini aktiv \u015f\u0259kild\u0259 m\u0259hv etm\u0259y\u0259 ba\u015flad\u0131 ki, bu da h\u0259r\u0259k\u0259t poz\u011funluqlar\u0131na v\u0259 dig\u0259r klinik simptomlara s\u0259b\u0259b oldu.<\/p>\n","protected":false},"excerpt":{"rendered":"
Karolinska \u0130nstitutunun aliml\u0259ri qocalm\u0131\u015f onur\u011fa beynind\u0259 g\u00f6zl\u0259nilm\u0259z bir qoruyucu mexanizm k\u0259\u015ff edibl\u0259r: onun \u00f6z immun h\u00fcceyr\u0259l\u0259ri sinir lifl\u0259rin\u0259 d\u0259y\u0259n z\u0259r\u0259rin qar\u015f\u0131s\u0131n\u0131 alma\u011fa k\u00f6m\u0259k edir. T\u0259dqiqat\u0131n n\u0259tic\u0259l\u0259ri Nature Neuroscience jurnal\u0131nda d\u0259rc edilib. Ya\u015fla, beyin v\u0259 b\u0259d\u0259n aras\u0131nda siqnal \u00f6t\u00fcr\u0259n onur\u011fa beyni t\u0259dric\u0259n struktur b\u00fct\u00f6vl\u00fcy\u00fcn\u00fc itirir. Sinir lifl\u0259rini \u0259hat\u0259 ed\u0259n qoruyucu t\u0259b\u0259q\u0259 olan miyelin x\u00fcsusil\u0259 h\u0259ssasd\u0131r. M\u00fcxt\u0259lif […]<\/p>\n","protected":false},"author":3,"featured_media":61030,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,41],"tags":[],"class_list":["post-79565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-media","category-life"],"yoast_head":"\n